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Sickle cell anemia is

Characterized by elongated sickle like RBCs with a nucleus
An autosomal linked dominant trait
Caused by substitution of valine by glutamic acid in the β globin chain of haemoglobin
Caused by a change in a single base pair of DNA
Additional Questions

Which one of the following conditions correctly describes the manner of determining the sex in the given example?

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Two genes R and Y are located very close on the chromosomal linkage map of maize plant. When RRYY and rryy genotypes are hybridized, the F2 segregation will show:

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Two pea plants were subjected cross pollination. Of the 183 plants produced in the next generation, 94 plants were found to be tall and 89 plants were found to be dwarf. The genotypes of the two parental plants are likely to be

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If two pea plants having red (dominant) coloured flowers with unknown genotypes are crossed, 75% of the flowers are red and 25% are white. The genotypic constitution of the parents having red coloured flowers will be

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In a given plant, red colour (R) of fruits is dominant over white fruit (r); and tallness (T) is dominant over dwarfness (t). If a plant with genotype RrTt is crossed with a plant of genotype rrtt, what will be the percentage of tall plants with red fruits in the next generation?

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In Mendel's experiments with garden pea, round seed shape (RR) was dominant over wrinkled seeds (rr), yellow cotyledon (YY) was dominant over green cotyledon (yy). What are the expected phenotypes in the F2 generation of the cross RRYY × rryy?

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Which of the following pair of features is a good example of polygenic inheritance?

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The Genetic deficiency of ADH-receptor leads to

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Genes for cytoplasmic male sterility in plants are generally located in:

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Sickle cell anemia is

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